DIRECTOR’S SPOTLIGHT

Jane M. Simoni, Ph.D.
Associate Director for Behavioral and Social Sciences Research and Director, Office of Behavioral and Social Sciences Research

OBSSR Advances Health Behavior Theories
This month’s Director’s Spotlight focuses on NIH’s role in transforming mental health care through research and discovery. Andrea Beckel-Mitchener, Ph.D., Acting Director of the National Institute of MenDespite the well-known Lewin’s Maxim—“There is nothing as practical as a good theory” (McCain, 2016)—many health researchers still struggle to understand or appreciate the utility of theory. I recall mentoring early-stage investigators who quipped that the only use for theory was to impress grant application reviewers, failing to grasp how theory could actually improve their research.

Put simply, theories are systematic ways of understanding complex phenomena. Health behavior theories (HBTs) describe interrelationships among concepts that explain or predict human behavior and behavior change (Simoni et al., 2018; Riley et al., 2011).

Why Health Behavior Theories Matter
HBTs provide a roadmap for designing interventions that are grounded in the science of behavior change and maintenance. They point to constructs that may moderate or mediate an intervention’s effect on health outcomes. Understanding who benefits from intervention strategies—and who does not—and the precise mechanisms through which they are operating can help us design implementation strategies that ensure effectiveness for everyone. Additionally, employing common theories contributes to a shared language that helps us synthesize research findings and refine theories.

How Do Adults with Diabetes Use Technology to Manage and Support Their Health?

Many of us struggle to consistently engage in healthy habits that optimize our health. For people with a chronic illness like diabetes, the challenge is even greater. As digital health tools become increasingly integrated into chronic disease management, it is critical to understand how patients use and benefit from these technologies.

What were the researchers studying and why?

For adults with diabetes, daily self-management is essential to reducing such complications as nerve damage, kidney failure, and stroke. Key self-management behaviors include taking medications as prescribed, eating a healthy diet, monitoring blood glucose and blood pressure, and getting adequate sleep. However, navigating these routine behaviors can be challenging, and long-term maintenance frequently is a struggle. Clinical trials that show short-term success often see a decline in effectiveness once interventions end, and long-term behavior maintenance rarely is evaluated. Tools like continuous glucose monitors, mobile apps, and activity trackers offer promise for managing diabetes, but their impact on and use in managing health behaviors are not fully understood. This study aimed to explore how adults with type 1 and type 2 diabetes use mobile apps and wearable devices to support their daily health management behaviors.

NIH Will Stop Posting Notices of Funding Opportunities in the NIH Guide for Grants and Contracts in FY2026

Since 2005, the National Institutes of Health (NIH) has posted all grant and cooperative agreement notices of funding opportunities (NOFOs) both on Grants.gov, a federal-wide portal for discretionary funding opportunities, and in the NIH Guide for Grants and Contracts (NIH Guide). Both have served as official sources for NIH NOFOs. This Notice informs the extramural community that, beginning in fiscal year 2026, NIH will no longer post NOFOs in the NIH Guide. Grants.gov will serve as NIH’s single official source for grant and cooperative agreement funding opportunities. The NIH Guide will continue to be used for policy and informational notices.

No-Cost Extension Functionality in eRA Commons Re-enabled

This notice provides an update on the guidance issued in NOT-OD-25-110. Effective with the issuance of this Guide Notice, NIH has re-enabled the No-Cost Extension functionality within eRA Commons. Recipients may resume initiating first no-cost extensions in eRA Commons in accordance with the NIH Grants Policy Statement, Section 8.1.1.3. Requests that were previously submitted via the prior approval module will not be reviewed, and recipients will need to initiate the first no-cost extension within the Status module by using the Extension action.

Deconstructing Reductionist Understandings of Distinctive Religious Minorities’ Health Decision-Making During COVID-19: The Plain Anabaptist Case

Join the Social, Behavioral, & Economic COVID Coordinating Center (SBE-CCC) for a free public webinar on August 28, 2025, from 3:00 to 4:00 p.m. ET. This presentation covers a large-scale project that interviewed a plain Anabaptist population and presents organized themes revealing how individuals navigated competing institutional pressures across family, church, economic, and government structures.

Foundation for the National Institutes of Health Seeking Concepts for New Approach Methodologies Pilot Projects

The Foundation for the National Institutes of Health (FNIH) is inviting the scientific community to submit project concepts to help us study new approach methodologies. The goal is to build scientific confidence in human-based research models, with a focus on regulatory acceptance. FNIH is looking for in vitro, in silico, and in chemico research models that are developed enough to undergo a detailed evaluation to determine their readiness for validation and qualification, including identifying if additional studies and data are needed. To be considered during the first cycle of review, applications must be submitted by 8 p.m. ET on August 31, 2025. Applications received after the August 31 deadline will be considered on a rolling basis through December 31, 2025.

Adolescent Brain Cognitive Development Webinar: Inside Adolescence: Substance Use Patterns, Predictions, Risk, and Resilience in the ABCD Study®

Join the Adolescent Brain Cognitive Development (ABCD) Study® for a free webinar on September 8, 2025. Experts will share research findings on early substance use and explore potential protective factors that could prevent or delay it. This webinar will be held twice to accommodate attendees in different time zones, first from 5:00 to 6:00 p.m. ET and then from 8:00 to 9:00 p.m. ET. Registration is encouraged, and Spanish interpretation will be available during both sessions.

NIH Releases Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs

NIH has released NOT-OD-25-138, a request for information regarding publication costs. NIH aims to maximize the value of each research grant, and as such, NIH grantees should utilize as much of their grant funds as possible for research activities. Although NIH recognizes the value of disseminating and publishing findings, journals with large publishing fees can lead awardees to pay unreasonably high fees using their NIH awards, which lessens the funds available for conducting research and burdens American taxpayers. NIH seeks information from all interested individuals and communities, including, but not limited to, researchers, universities and research institutions, librarians, scientific societies, publishers, and other members of the public. Responses will be accepted through September 15, 2025.

NIH ECHO Symposium: Translating Science to Action

The NIH Environmental influences on Child Health Outcomes (ECHO) Program is hosting the inaugural “NIH ECHO Symposium: Translating Science to Action” on September 15, 2025, both virtually and on the NIH main campus in Bethesda, Maryland. This free, 1-day interdisciplinary event seeks to translate child health research into action by informing intervention programs, health policies, and clinical practice.

National Institute of Nursing Research 40th Anniversary Scientific Symposium—Advancing Nursing Science to Improve Health for All: NINR’s Impact

The National Institute of Nursing Research (NINR) invites you to attend its 40th Anniversary Scientific Symposium on September 17, 2025, at the Masur Auditorium, NIH Clinical Center, from 8:00 a.m. to 4:45 p.m. ET. The symposium and accompanying poster session, titled “Advancing Nursing Science to Improve Health for All: NINR’s Impact,” will celebrate four decades of excellence in nursing research and showcase NINR-funded investigators who are leading scientific discoveries of innovative systems and models of care, breakthroughs in disease prevention and health promotion, and advances in population and community health that tackle the everyday challenges that matter most to people and their health.

National Heart, Lung, and Blood Institute Workshop: Lung as the Gateway for Environmental Exposures in Pulmonary and Cardiovascular Disease

The National Heart, Lung, and Blood Institute is hosting a virtual workshop on October 14 and 15, 2025, from 10:00 a.m. to 4:00 p.m. ET on both days. This workshop will bring together basic scientists, primary care physicians, pediatricians, neonatologists, pulmonologists, pharmacists, epidemiologists, environmentalists, toxicologists, implementation scientists, data scientists, community representatives, and more to discuss the unique role of the lung as the interface with the environment and the pulmonary and cardiovascular consequences of inhalational exposures.

Blueprint MedTech Translator (UG3/UH3 – Clinical Trial Optional)

Open Date (Earliest Submission Date): August 29, 2025

Notice of Special Interest (NOSI): Understanding and Addressing Weight Stigma, Bias, and Discrimination to Promote Health for All

Next Available Due Date: See the relevant notice of funding opportunity under the heading “Applications and Submission Information.”

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