ORWH and the ACRWH are seeking comments from the scientific community, professional societies, and the general public to assist in identifying gaps in research and clinical practice pertaining to the topics mentioned below. Submissions must be emailed to Elizabeth Barr, Ph.D. (WHCC@od.nih.gov), by September 15, 2021. 


In response to a congressional request to address NIH efforts related to women’s health research, the Office of Research on Women’s Health (ORWH), in conjunction with the Advisory Committee on Research on Women’s Health (ACRWH), will be hosting an event titled “Advancing NIH Research on the Health of Women: A 2021 Conference.” The key topics to be discussed, as identified by Congress, are (1) clinical practices related to rising maternal morbidity and mortality rates; (2) increasing rates of chronic debilitating conditions in women; and (3) stagnant cervical cancer survival rates. Learn more about these issues below.

Maternal Morbidity and Mortality

Maternal morbidity and mortality is a public health crisis in the United States, with an estimated 6 in 10 maternal deaths being preventable. During 2011–2015, the United States had nearly twice the live birth maternal mortality rate as peer countries, such as Canada and the United Kingdom. This rise in maternal mortality is even more pronounced among women of color, including Black, American Indian/Alaska Native, and Hispanic women. These racial and ethnic disparities are influenced by structural racism, implicit bias, and racially biased policies and practices, with neither education nor higher socioeconomic status mitigating the elevated risks.

Chronic Debilitating Conditions in Women

Rates of chronic debilitating conditions, such as chronic obstructive pulmonary disease (COPD), affecting women in the U.S. are on the rise, and chronic diseases are more common in women than men. However, there is a limited understanding of the impact of sex and gender influences on the outcomes of individuals with chronic diseases. Current challenges include lack of research on rare diseases that are more prevalent in women and lower specificity, sensitivity, and efficacy of diagnostic tests. Also, disparities exist among underserved racial and ethnic groups. For example, Black women are 20% more likely to die from heart disease than White women.

Stagnant Cervical Cancer Survival Rates

In the U.S., there are approximately 12,000 new cases of cervical cancer per year. Despite increased cervical cancer prevention efforts through human papillomavirus (HPV) vaccination and cervical cancer screening, the incidence of and mortality rate from cervical cancer have remained stable over the past two decades. There are also significant racial and ethnic disparities related to cervical cancer. For example, Black and Hispanic women in the U.S. are diagnosed more frequently than women of other races and ethnicities in the U.S. and are less likely to survive.

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